PUBLICATIONS

ASYMMETRIC REDOX-NEUTRAL RADICAL CYCLIZATION CATALYZED BY FLAVIN-DEPENDENT ‘ENE’-REDUCTASES

Chemrxiv,2019

Michael J. Black, Kyle F. Biegasiewicz, Andrew J. Meichan, Daniel G. Oblinsky, Bryan Kudisch, Gregory Scholes, Todd Hyster

PHOTOEXCITATION OF FLAVOENZYMES ENABLES A STEREOSELECTIVE RADICAL CYCLIZATION

Science 2019, 364, 1166–1169 

 Kyle F. Biegasiewicz, Simon J. Cooper, Xin Gao, Daniel G. Oblinsky, Ji Hye Kim, Samuel E. Garfinkle, Leo A. Joyce, Braddock A. Sandoval, Gregory D. Scholes, Todd K. Hyster.

RADICAL BIOCATALYSIS: USING NON-NATURAL SINGLE ELECTRON TRANSFER MECHANISMS TO ACCESS NEW ENZYMATIC FUNCTIONS

 Todd K. Hyster

Synlett 2019, 30, A–G

PHOTOENZYMATIC CATALYSIS ENABLES RADICAL-MEDIATED

KETONE REDUCTION IN 'ENE'-REDUCTASES

Angew. Chem. Int. Ed., DOI: 10.1002/anie.201902005

Braddock A. Sandoval, Sarah I. Kurtoic, Megan M. Chung, Kyle F. Biegasiewicz, Todd K. Hyster

BIOCATALYTIC HYDROGEN ATOM TRANSFER: AN INVIGORATING APPROACH TO FREE-RADICAL REACTIONS

Yuji Nakano, Kyle F Biegasiewicz, Todd K Hyster

Curr. Opin. Chem. Biol., 2019, 49, 16-24.

ENANTIOSELECTIVE HYDROGEN ATOM TRANSFER: DISCOVERY OF CATALYTIC PROMISCUITY IN FLAVIN-DEPENDENT ‘ENE’-REDUCTASES

Braddock A. Sandoval
Andrew J. Meichan, Todd K. Hyster

J. Am. Chem. Soc. 2017, 139, 11313. 

ACCESSING NON-NATURAL REACTIVITY BY IRRADIATING NICOTINAMIDE-DEPENDENT ENZYMES WITH LIGHT

Nature 2016, 540, 414.

Megan A. Emmanuel, Norman R. Greenberg, Daniel G. Oblinsky, Todd K. Hyster

GENETIC OPTIMIZATION OF METALLOENZYMES: ENHANCING ENZYMES FOR NON-NATURAL REACTIONS

Todd K. Hyster, Thomas R. Ward

Angew. Chem. Int. Ed. 2016, 55, 7344.