THE HYSTER GROUP
Developing Biocatalysts For The 21st Century
An Efficient Synthesis of the Bicyclic Darunavir Side Chain Using Chemoenzymatic Catalysis
Paul S. Riehl, Jesmine Lim, James D. Finnigan, Simon J. Charnock, and Todd K. Hyster
Workflow for Biocatalytic Reaction Performance Prediction and Analysis
ADAPTIVE ENZYME DISCOVERY
In an effort to develop more efficient and selective synthetic routes of valuable organic molecules, our group is focused on discovering versatile biocatalysts that can be used to effect a variety of synthetic reactions.
Our research emphasis is on the convergence of small molecule catalysis with enzymes, whereby the benefits of each are harnessed to uncover previously unknown chemical transformations with high selectivity.